Prebys Ventures invests in San Diego-based companies driving innovation in technology, life sciences, and healthcare.

From developing breakthrough medical treatments to advancing technologies that improve patient care, our portfolio reflects the region’s entrepreneurial talent and potential. By investing in promising companies at various stages of growth, we aim to strengthen San Diego’s innovation ecosystem, attract new investment, and create lasting economic opportunities that benefit our region.


Aero RX Therapeutics

Aero RX Therapeutics is a clinical-stage biopharmaceutical company, developing best-in-class combination treatments for inhalation delivery via nebulization in Chronic Obstructive Pulmonary Disease (“COPD”) for underserved, high risk, older COPD patients.

Aspen Neuroscience

Aspen Neuroscience is a clinical-stage, private biotechnology company focused on personalized (autologous) cell therapies to address diseases with high unmet medical need, beginning with autologous neuron replacement for Parkinson’s disease (PD).

Condor 

Condor is the financial intelligence platform for life sciences that unifies clinical, vendor, and finance data. 

Crystalys Therapeutics

Crystalys Therapeutics is a biotechnology company specializing in the development and commercialization of therapeutic products. develops therapies for rheumatic diseases and other conditions.

Protalys Therapeutics

Protalys Therapeutics is at the forefront of addressing challenges with Proteolysis Targeting Chimeras (PROTACs). The company’s approach may solve issues associated with many proposed solid tumor targets, including targets considered ​“undruggable.” 

Resolute Science 

Resolute Science is a preclinical oncology biotech developing a new type of targeted drug conjugate for difficult-to-treat solid tumors. 

Truvian Health

Truvian Health is a diagnostics company developing a benchtop blood-testing system designed to bring much of a traditional clinical laboratory into a physician’s office, pharmacy, clinic, or other point-of-care setting.

Welby Health 

Welby Health is a healthcare technology and patient engagement provider that offers a platform for remote patient monitoring (RPM) and chronic care management (CCM)